Moving with purpose and direction: transcription factor movement and cell fate determination revisited

by Shyam Gundu, Naheed Tabassum, Ikram Blilou
Open Access Year: 2020 DOI: https://doi.org/10.1016/j.pbi.2020.08.003

Bibliography

Gundu, S., Tabassum, N., and Blilou, I., 2020. Moving with purpose and direction: transcription factor movement and cell fate determination revisited. Current Opinion in Plant Biology57, pp.124-132.

Abstract

Cell diversity in a multicellular organism relies on cell-cell communication where cells must receive positional information as input signals to adopt their proper cell fate in the right place and at the right time. This process is achieved through triggering signaling cascades that drive cellular changes during development. In plants, signaling through mobile transcription factors (TF) plays a central role in development. Rather than acting cell-autonomously and exclusive to their expression domains, many TFs move between cells and deploy regulatory networks and cell type-specific effectors to achieve their biological functions. Here, we highlight a few examples of mobile TFs central to cell fate specification in Arabidopsis.

Keywords

Cell fate specification cell non-autonomous transcription factors